Propylparaben → HCID 178439434, compound

HRID 1758456Notes

Reaction equation

HRID 1758456 reaction equation
[OH:1][C:2]1[CH:13]=[CH:12][C:5]([C:6]([O:8]CCC)=[O:7])=[CH:4][CH:3]=1.[OH-].[Na+].O.O.[C:18]([O-])(=O)[CH3:19].[Zn+2:22].[C:23]([O-:26])(=[O:25])[CH3:24].[Na]>O>[CH2:23]([C:4]1[CH:3]=[C:2]([OH:1])[CH:13]=[CH:12][C:5]=1[C:6]([O-:8])=[O:7])[CH2:18][CH3:19].[CH2:5]([C:4]1[CH:3]=[C:2]([OH:1])[CH:13]=[CH:12][C:24]=1[C:23]([O-:26])=[O:25])[CH2:6][CH3:18].[Zn+2:22]

Participants

6

Reactant 4

HCID 7175PropylparabenHCID 14798Sodium HydroxideHCID 2724192Zinc acetate (USP)HCID 5360545Sodium

Product 1

HCID 178439434HCID 178439434, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To a suspension of 20.7 parts (0.155 mole) of propyl p-hydroxybenzoate in 40 parts of water that had been cooled to 0°-10° C. was slowly added a 50% aqueous sodium hydroxide solution until the pH of the resulting solution was 11.9. A solution of 12.6 parts (0.06 mole) of zinc acetate dihydrate in 200 parts of water was added to the sodium salt solution. The white precipitate that formed was separated by filtration, washed with cold water, and dried. There was obtained 23.9 parts of zinc bis(propyl p-hydroxybenzoate).

Workup

  1. temperaturehad been cooled to 0°-10° C.
  2. customThe white precipitate that formed
  3. customwas separated by filtration
  4. washwashed with cold water
  5. customdried

Sources & evidence

ORD record
ord-e365d8cc40974d669cd5a5ed489685d2
Source dataset
uspto-grants-1983_02
Patent number
US04373953

Reaction notes

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