Hydrochloric Acid → HCID 57353946, compound

HRID 1758477Notes

Reaction equation

HRID 1758477 reaction equation
[CH:1]1[C:14]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=[C:8]3[CH2:15][CH2:16][CH2:17][CH2:18][CH:7]3[O:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH2:19]=O.Cl>C(O)=O>[CH3:19][CH:17]1[CH2:16][CH2:15][C:8]2=[CH:9][CH:10]=[N:11][CH:12]=[CH:13][C:14]3[CH:1]=[CH:2][CH:3]=[CH:4][C:5]=3[O:6][CH:7]2[CH2:18]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 70511564HCID 70511564, compound

Product 1

HCID 57353946HCID 57353946, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Conditions

Temperature
100 °C

Procedure

1 gram of 6,7,8,9-tetrahydro-5H-dibenz(b,i)(1,6)oxazecine was mixed with 4 ml formic acid and 3.8 ml of 37% formalin. This mixture was heated for 1 hour at 100° C. After cooling 0.5 ml of concentrated hydrochloric acid was added and the reaction mixture was evaporated. The residue was then dissolved in dilute NaOH, and the mixture extracted with ether. The ether extract was washed, dried and evaporated to dryness.

Workup

  1. additionwas added
  2. customthe reaction mixture was evaporated
  3. dissolutionThe residue was then dissolved in dilute NaOH
  4. extractionthe mixture extracted with ether
  5. extractionThe ether extract
  6. washwas washed
  7. customdried
  8. customevaporated to dryness

Sources & evidence

ORD record
ord-d7d8d00ae37349b19b034f4aed1e7c88
Source dataset
uspto-grants-1983_02
Patent number
US04374133

Reaction notes

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