2-Carbamoyl-4,5-difluorobenzoic acid → 5,6-Difluoroisoindoline-1,3-dione

참여 물질

반응 단계

One part of the 4,5-difluorophthalamic acid was heated to 170° C. for a period of 30 minutes, then cooled, dissolved in toluene and crystallized therefrom. The crystalline product was separated by filtration to yield 0.56 parts of 4,5-difluorophthalimide, having a melting range of 154°-156° C. The structure was confirmed by C13 nuclear magnetic resonance analysis.

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