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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1758578Generated: November 5, 2026

Formaldehyde → 1-Phenyl-1-propanone

https://huagongshe.com/reaction/1758578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantAcetophenoneHCID 7410—
SolventIsobutanolHCID 6560—
Product1-Phenyl-1-propanoneHCID 7148—

Reaction Steps

0.5 liter per hour of a mixture of acetophenone and a 30% strength solution of formaldehyde in isobutanol (the molar ratio of acetophenone to formaldehyde being 8:1) was reacted at 180° C., under 30 bar H2 pressure, in the apparatus, and over the catalyst, described in Example 1. The yield of propiophenone obtained was 52.8%, based on formaldehyde employed.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04374274
Source datasetuspto-grants-1983_02
ORD IDord-a6637c0541964cd1b0e5c20de561df1a
Source noteuspto-grants-1983_02