Hydrochloric Acid → Phenol, 4-[1-(4-aminophenyl)-1-methylethyl]-

HRID 1758584Notes

Reaction equation

HRID 1758584 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1)([CH3:3])=[CH2:2].[NH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.Cl>>[OH:10][C:7]1[CH:8]=[CH:9][C:4]([C:1]([C:15]2[CH:16]=[CH:17][C:12]([NH2:11])=[CH:13][CH:14]=2)([CH3:3])[CH3:2])=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6115Aniline2×HCID 584247p-Isopropenylphenol2×

Product 1

HCID 11148864Phenol, 4-[1-(4-aminophenyl)-1-methylethyl]-Yield 94%

Conditions

Temperature
150 °C

Procedure

A mixture of 13.4 g (0.1 mole) of p-isopropenyl phenol monomer and 18.6 g (0.2 mole) of aniline was stirred at 150° C. To the mixture was added 0.50 g of a solution obtained by adding 1.28 g of 35% hydrochloric acid to 93 g of aniline and stirring the mixture well (to be referred to as a catalyst solution) (0.0018 mole of catalyst per mole of p-isopropenyl phenol), and the reaction was carried out for 3 hours. Gas-chromatographic analysis of the reaction mixture showed that 21.3 g (yield 94%) of 2-(4'-hydroxyphenyl)-2-(4'-aminophenyl)-propane of the formula ##STR11## was formed.

Workup

  1. customobtained
  2. stirringstirring the mixture well (

Sources & evidence

ORD record
ord-9d9a9c1a89624f178eccb22eaa34549d
Source dataset
uspto-grants-1983_02
Patent number
US04374272

Reaction notes

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