Methylamine → HCID 20402227, compound

HRID 1758598Notes

Reaction equation

HRID 1758598 reaction equation
[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH2:7][S:8][CH2:9][CH2:10][NH2:11].CC1NC=NC=1CSC[CH2:21][NH:22][C:23]1[C:27](OC)=[N:26][S:25](=[O:30])[N:24]=1.CN>>[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH2:7][S:8][CH2:9][CH2:10][NH:11][C:27]1[C:23]([NH:22][CH3:21])=[N:24][S:25](=[O:30])[N:26]=1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 6655684-(((2-Aminoethyl)thio)methyl)-5-methylimidazoleHCID 20402235HCID 20402235, compound

Product 1

HCID 20402227HCID 20402227, compound

Procedure

A solution of 3,4-dimethoxy-1,2,5-thiadiazole 1-oxide obtained from the above Step A is reacted with an equimolar amount of 2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethylamine and the resulting 3-{2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethylamino}-4-methoxy-1,2,5-thiadiazole 1-oxide is treated with an excess of methylamine, and the title compound is thereby produced.

Sources & evidence

ORD record
ord-88aa7239df0846f79bcfd705fa7c82db
Source dataset
uspto-grants-1983_02
Patent number
US04374248

Reaction notes

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