Methylamine → HCID 178482514, compound

HRID 1758607Notes

Reaction equation

HRID 1758607 reaction equation
CO[C:3]1[C:7](OC)=[N:6][S:5](=[O:11])(=[O:10])[N:4]=1.[CH3:12][N:13]([CH2:15][C:16]1[O:20][C:19]([CH2:21][S:22][CH2:23][CH2:24][NH2:25])=[CH:18][C:17]=1[CH3:26])[CH3:14].[CH3:27][NH2:28]>CO>[CH3:14][N:13]([CH2:15][C:16]1[O:20][C:19]([CH2:21][S:22][CH2:23][CH2:24][NH:25][C:7]2[C:3]([NH:28][CH3:27])=[N:4][S:5](=[O:10])(=[O:11])[N:6]=2)=[CH:18][C:17]=1[CH3:26])[CH3:12]

Participants

5

Reactant 3

HCID 6329MethylamineHCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxideHCID 131251172-[(5-Dimethylaminomethyl-4-methyl-2-furyl)methylthio]ethylamine

Product 1

HCID 178482514HCID 178482514, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

When a methanol suspension of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide is reacted with an equimolar amount of 2-[(5-dimethylaminomethyl-4-methyl-2-furyl)methylthio]ethylamine [prepared in Step C] and the resultant 3-{2-[(5-dimethylaminomethyl-4-methyl-2-furyl)methylthio]ethylamino}-4-methoxy-b 1,2,5-thiadiazole 1,1-dioxide is treated with an excess of methylamine, the title compound is produced.

Sources & evidence

ORD record
ord-ec24a99080e446f6a53fa99aa9fdeeb2
Source dataset
uspto-grants-1983_02
Patent number
US04374248

Reaction notes

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