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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1758630Generated: October 30, 2026

Ammonia → HCID 178456954, compound

https://huagongshe.com/reaction/1758630

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant3,4-Dimethoxy-1,2,5-thiadiazole 1-oxideHCID 12913947—
ReactantHCID 178458092HCID 178458092—
ReactantHCID 178494325HCID 178494325—
ProductHCID 178456954HCID 178456954—

Reaction Steps

When a methanolic solution of 2-[(guanidinothiazol-4-yl)methylthio]propylamine is reacted with 3,4-dimethoxy-1,2,5-thiadiazole 1-oxide [prepared in Example 4, Step A], and the resultant 3-{2-[(2-guanidinothiazol-4-yl)methylthio]propylamino}-4-methoxy-1,2,5-thiadiazole 1-oxide is treated with excess ammonia by the procedure in Example 35, the title compound is thereby produced.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04374248
Source datasetuspto-grants-1983_02
ORD IDord-54090d1fd5a04c4f9aa84bcd2eff1e07
Source noteuspto-grants-1983_02