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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1758699Generated: October 30, 2026

4-Bromo-4'-hydroxybiphenyl → 4'-Hydroxy-4-biphenylcarbonitrile

https://huagongshe.com/reaction/1758699

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-4'-hydroxybiphenylHCID 95093—
ReactantHCID 178418546HCID 178418546—
Product4'-Hydroxy-4-biphenylcarbonitrileHCID 140610—

Reaction Steps

4'-Bromo-4-hydroxybiphenyl is reacted with copper (I) cyanide to obtain 4'-cyano-4-hydroxybiphenyl (this substance is known), which is then reacted with a β-alkyloxyethylbromide in the presence of an alkaline material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04374748
Source datasetuspto-grants-1983_02
ORD IDord-fb4dc43360df44e59e6a691aef465d5f
Source noteuspto-grants-1983_02