HCID 13014421, compound → HCID 20519703, compound

HRID 1758952Notes

Reaction equation

HRID 1758952 reaction equation
C([C:3]1[C:4](=[O:18])[NH:5][C:6](=[O:17])[N:7]([C:9]2[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=2[CH3:16])[CH:8]=1)#N>Br>[CH3:16][C:10]1[CH:11]=[CH:12][CH:13]=[C:14]([CH3:15])[C:9]=1[N:7]1[CH:8]=[CH:3][C:4](=[O:18])[NH:5][C:6]1=[O:17]

Participants

3

Reactant 1

HCID 13014421HCID 13014421, compound

Product 1

HCID 20519703HCID 20519703, compound

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

A mixture of 5-cyano-1-(2,6-dimethylphenyl)uracil (0.01 mol) and 30 ml of 48% HBr is heated at reflux for about 10 hours. After cooling, the solid product is collected by filtering, washed with water and dried to yield 1-(2,6-dimethylphenyl)uracil.

Workup

  1. temperatureis heated
  2. temperatureat reflux for about 10 hours
  3. temperatureAfter cooling
  4. customthe solid product is collected
  5. filtrationby filtering
  6. washwashed with water
  7. customdried

Sources & evidence

ORD record
ord-fd4317e9820d43d08a40ef0d2a60f8ca
Source dataset
uspto-grants-1982_07
Patent number
US04338318

Reaction notes

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