Hydrogen Peroxide → HCID 20533546, compound

Participants

Reaction Steps

Refer to Chart F. One equivalent of 5-mercapto-4-phenyl-4H-1,2,4-triazole-3-methanol (Formula XXIII of Chart B, R24 is hydroxymethyl, R5 is phenyl, n is zero) is prepared according to Chart B. One equivalent of this compound is treated with sodium hydroxide and bromoethane. This product is then oxidized with aqueous hydrogen peroxide to yield 5-methylsulfinyl-4-phenyl-4H-1,2,4-triazole-3-methanol. This product is further oxidized by treating it with m-chlorobenzoic acid at 25° C. for 24 hrs to yield the titled product.

Provenance & Evidence