Hydrogen Peroxide → HCID 20533546, compound

HRID 1759035Notes

Reaction equation

HRID 1759035 reaction equation
[SH:1][C:2]1[N:3]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:4]([CH2:7][OH:8])=[N:5][N:6]=1.[OH-:15].[Na+].Br[CH2:18]C.OO>>[CH3:18][S:1]([C:2]1[N:3]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:4]([CH2:7][OH:8])=[N:5][N:6]=1)=[O:15]

Participants

5

Reactant 4

HCID 784Hydrogen PeroxideHCID 6332Ethyl BromideHCID 14798Sodium HydroxideHCID 178520016HCID 178520016, compound

Product 1

HCID 20533546HCID 20533546, compound

Procedure

Refer to Chart F. One equivalent of 5-mercapto-4-phenyl-4H-1,2,4-triazole-3-methanol (Formula XXIII of Chart B, R24 is hydroxymethyl, R5 is phenyl, n is zero) is prepared according to Chart B. One equivalent of this compound is treated with sodium hydroxide and bromoethane. This product is then oxidized with aqueous hydrogen peroxide to yield 5-methylsulfinyl-4-phenyl-4H-1,2,4-triazole-3-methanol. This product is further oxidized by treating it with m-chlorobenzoic acid at 25° C. for 24 hrs to yield the titled product.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-165c951f35754cbd8a7d60f123585f4b
Source dataset
uspto-grants-1982_07
Patent number
US04338453

Reaction notes

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