Methanol → tert-Butyl 4-(5-aminopyridin-2-yl)piperazine-1-carboxylate

HRID 175907Notes

Reaction equation

HRID 175907 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([N+:20]([O-:21])=[O:22])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH3:23][OH:24].[CH3:27][CH2:28][O:29][C:30]([CH3:31])=[O:32].[H:25][H:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 887MethanolHCID 8857Ethyl AcetateHCID 16217943tert-Butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylateHCID 178418361HCID 178418361, compound

Product 1

HCID 17999304tert-Butyl 4-(5-aminopyridin-2-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-c973acbb349741acbec6ba80055deaa0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…