Dichloromethane → 3-(1,3-Benzoxazol-2-yl)-5-[1-(4-piperidyl)triazol-4-yl]pyridin-2-amine

HRID 175909Notes

Reaction equation

HRID 175909 reaction equation
[Cl:42][CH2:43][Cl:44].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH2:8][c:9]1[c:10](-[c:33]2[o:34][c:35]3[c:36]([n:37]2)[cH:38][cH:39][cH:40][cH:41]3)[cH:11][c:12](-[c:15]2[n:16][n:17][n:18]([CH:20]3[CH2:21][CH2:22][N:23]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH2:24][CH2:25]3)[cH:19]2)[cH:13][n:14]1>>[NH2:8][c:9]1[c:10](-[c:33]2[o:34][c:35]3[c:36]([n:37]2)[cH:38][cH:39][cH:40][cH:41]3)[cH:11][c:12](-[c:15]2[n:16][n:17][n:18]([CH:20]3[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]3)[cH:19]2)[cH:13][n:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67388898Tert-butyl 4-[4-[6-amino-5-(1,3-benzoxazol-2-yl)-3-pyridyl]triazol-1-yl]piperidine-1-carboxylate

Product 1

HCID 576870133-(1,3-Benzoxazol-2-yl)-5-[1-(4-piperidyl)triazol-4-yl]pyridin-2-amine

Sources & evidence

ORD record
ord-bf40d5a4554e4d2b9108a44983018b28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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