Ethanol → HCID 23701872, compound

HRID 1759170Notes

Reaction equation

HRID 1759170 reaction equation
[C:1]([CH2:4][PH:5](=[O:7])[O-:6])(=O)C.[Na+:8].[NH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[CH2:16](O)C>>[CH3:16][P:5]([C:4](=[N:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH3:1])(=[O:7])[O-:6].[Na+:8]

Participants

4

Reactant 3

HCID 702EthanolHCID 6115AnilineHCID 178473688HCID 178473688, compound

Product 1

HCID 23701872HCID 23701872, compound

Procedure

A mixture of sodium acetylmethylphosphinate (4.3 g) and aniline (3.2 ml) was dissolved in ethanol (200 ml) and allowed to stand for 72 hours over 4 A molecular sieve. The solution was filtered free of the solid phase, evaporated in vacuo and the residue was triturated with ether to give a pale brown solid (6.1 g). The nmr spectrum showed that the crude product contained an aromatic moiety.

Workup

  1. filtrationThe solution was filtered free of the solid phase
  2. customevaporated in vacuo
  3. customthe residue was triturated with ether

Sources & evidence

ORD record
ord-0c908ad2c73544a9a26d3525f113cf3c
Source dataset
uspto-grants-1982_07
Patent number
US04339443

Reaction notes

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