Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-hydroxyisoxazole | HCID 13117012 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 13117017 | HCID 13117017 | — |
Reaction Steps
A mixture containing 200 mg of 4-hydroxyisoxazole in 10 ml of acetone together with 1.5 equivalents of benzyl bromide and 1.5 equivalents of potassium carbonate is stirred at about 25° C. for five hours. The solid is filtered and the filtrate concentrated to an oil. The crude material is purified by chromatography on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04339588 |
|---|
| Source dataset | uspto-grants-1982_07 |
|---|
| ORD ID | ord-8b06d7e984b2497ea462637c04ad794f |
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| Source note | uspto-grants-1982_07 |
|---|
