Methanol → 4-Methoxybenzaldehyde

HRID 1759283Notes

Reaction equation

HRID 1759283 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][CH:3]=1.C[OH:11]>>[CH3:9][O:8][C:5]1[CH:6]=[CH:7][C:2]([CH:1]=[O:11])=[CH:3][CH:4]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 77314-Methylanisole

Product 1

HCID 312444-MethoxybenzaldehydeYield 97.3%

Procedure

In the same manner as in Example 1, p-methyl anisole is oxidized with use of an 80% by weight aqueous solution of methanol in place of methanol, affording anisaldehyde in a yield of 97.3%. With use of cerium salt regenerated in the same manner as in Example 1 (and using an 80% by weight methanol aqueous solution in place of methanol) for the second oxidation, anisaldehyde is obtained in a yield of 94.3%.

Sources & evidence

ORD record
ord-f1b1d6cf4eb7448f85babc624ca0beef
Source dataset
uspto-grants-1982_07
Patent number
US04339607

Reaction notes

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