Hydrochloric Acid → p-((1,1,2,2-Tetrafluoroethyl)thio)aniline

Participants

Reaction Steps

A mixture of 5 g of XI and 40 ml of 6 N hydrochloric acid was heated under reflux for 4 hours. The mixture was diluted with 200 ml of water and filtered. The filtrate was concentrated to dryness and the solid residue was triturated with ether and filtered to give 4-(1,1,2,2-tetrafluoroethylthio)aniline (XII) as a hydrochloride salt.

Provenance & Evidence