HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 13023013, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Epibromohydrin | HCID 18430 | — |
| Reactant | 2-(6-Chloro-3-pyridazinyl)phenol | HCID 3018733 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 13023013 | HCID 13023013 | — |
Reaction Steps
A mixture of 3-chloro-6-(2-hydroxyphenyl)pyridazine (2.69 g.), epibromohydrin (4.5 ml.), anhydrous potassium carbonate (3.6 g.) and dry butane-2-one (100 ml.) was stirred and heated under reflux for 16 hours. The mixture was filtered and the filtrate was evaporated to dryness and the residue was twice recrystallized from ethanol to give 3-chloro-6-(2-epoxypropoxyphenyl)pyridazine, m.p. 118°-119°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04340733 |
| Source dataset | uspto-grants-1982_07 |
| ORD ID | ord-c7673871e70141e88e1fed2644ed4017 |
| Source note | uspto-grants-1982_07 |