Hydrofluoric Acid → 5-Tert-butyl-m-xylene

HRID 1759450Notes

Reaction equation

HRID 1759450 reaction equation
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([C:9]([CH3:12])([CH3:11])[CH3:10])=[CH:4][C:3]=1[CH3:13].F>C1(C)C=CC=C(C)C=1>[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH3:13].[CH3:8][C:7]1[CH:6]=[C:5]([C:9]([CH3:11])([CH3:10])[CH3:12])[CH:4]=[C:3]([CH3:13])[CH:2]=1

Participants

5

Reactant 2

HCID 14917Hydrofluoric AcidHCID 2203642-Bromo-5-tert-butyl-1,3-dimethylbenzene

Product 2

HCID 73785-Tert-butyl-m-xyleneHCID 684712-Bromo-m-xylene

Reagents, catalysts & solvents 1

HCID 7929M-XyleneSolvent

Procedure

contacting the 2-bromo-1,3-dimethyl-5-tertiary-butylbenzene with meta-xylene in the presence of hydrogen fluoride at a temperature of from about 30° C. to about 60° C. and a pressure of from about 20 psig to about 100 psig to form 2-bromo-1,3-dimethylbenzene and 1,3-dimethyl-5-tertiary-butylbenzene;

Workup

  1. customof from about 30° C. to about 60° C.

Sources & evidence

ORD record
ord-e26ba37ce2a745a9a9d91b4ce2957f95
Source dataset
uspto-grants-1982_07
Patent number
US04340757

Reaction notes

Loading…