HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → 3-Chloro-2,2,3-trifluoro-propionyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 3-Chloro-2,2,3-trifluoropropanoic acid | HCID 20531322 | — |
| Product | 3-Chloro-2,2,3-trifluoro-propionyl chloride | HCID 14122416 | — |
Reaction Steps
In a three-necked 2 l flask provided with a Vigreux column, a condenser, and a collecting flask were brought 325 g (2 moles) of 3-chloro-2,2,3-trifluoro-propionic acid (Org.Synth.Coll. 5, 239) and 562 g (4 moles) of benzoyl chloride. The mixture was heated so that the acid chloride distilled over slowly. The collected product was refluxed for 20 min to eliminate any residual hydrochloric acid. Finally the product was distilled at normal pressure. Yield: 280 g. Boiling point: 72°-74° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04341864 |
| Source dataset | uspto-grants-1982_07 |
| ORD ID | ord-c436943872e143dca8a6cbf920ea371e |
| Source note | uspto-grants-1982_07 |