HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 12152140, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 6-Chloro-3-nitropyridin-2-ylamine | HCID 2724035 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12152140 | HCID 12152140 | 88% |
Reaction Steps
2 g (0.012 mol) of 2-amino-6-chloro-3-nitropyridine, 30 ml of dioxane and 20 ml of water, and 1.8 g of pyrrolidine are charged to a fully equipped round-bottomed flask. The mixture is brought to 70° C. for one hour with stirring and then the mixture is poured onto an ice/water mixture with stirring. The precipitate formed is filtered off and dried. 2.2 g of yellow powder are obtained, Yd=88%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06837908B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-17aeeb893b0d457bb1e5746ba3ae935e |
| Source note | uspto-grants-2005_01 |