HCID 12152140, compound → HCID 12091771, compound

Participants

Reaction Steps

2 g of 2-amino-3-nitro-6-(pyrrolidin-1-yl)pyridine, synthesized according to the above procedure, 100 ml of ethanol and 0.5 g of palladium-on-charcoal are charged to a 300 ml autoclave. The mixture is reduced for one hour at a pressure of 8 bar with stirring. The catalyst is subsequently removed by filtration and then the filtrate is acidified with hydrochloric acid. After diluting with diisopropyl ether, the precipitate formed is filtered off and dried. 2.1 g of powder are obtained, Yd=87.1%.

Provenance & Evidence