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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1759711Generated: November 4, 2026

Trifluoroacetic acid → HCID 86594981, compound

https://huagongshe.com/reaction/1759711

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86594980HCID 86594980—
SolventDichloromethaneHCID 6344—
ProductHCID 86594981HCID 86594981136.4%

Reaction Steps

Hydrolysis of the ester is carried out as in the previous examples, but starting from 50 mg of 8-3 and twice 0.5 ml of TFA in 1.5 ml dichloromethane. 62 mg of 8-4 is obtained (in the form of the trifluoroacetic acid salt).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06838453B2
Source datasetuspto-grants-2005_01
ORD IDord-918e883650ab4d69b53ec76231918aed
Source noteuspto-grants-2005_01