p-Fluoronitrobenzene → HCID 22048125, compound

HRID 1759759Notes

Reaction equation

HRID 1759759 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[NH2:11][CH2:12][CH2:13][N:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[N:14]1([CH2:13][CH2:12][NH:11][C:2]2[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 9590p-FluoronitrobenzeneHCID 33944N-(2-Aminoethyl)piperidine

Product 1

HCID 22048125HCID 22048125, compound

Procedure

Using an analogous procedure to that described in Method 23, but starting from 4-fluoronitrobenzene and 1-(2-aminoethyl)piperidine, the product was obtained. NMR: 1.3 (m, 2H), 1.5 (m, 4H), 2.3 (m, 4H), 2.4 (t, 2H), 3.2 (m, 2H), 6.6 (d, 2H), 7.1 (m, 1H), 8.0 (d, 2H); MS (MH+): 250.

Workup

  1. customthe product was obtained

Sources & evidence

ORD record
ord-47e80ef3d8424ace8d2e9bc4eb6bc754
Source dataset
uspto-grants-2005_01
Patent number
US06838464B2

Reaction notes

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