HCID 178489097、化合物 → HCID 178489090、化合物

HRID 1760172ノート

反応式

HRID 1760172 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[NH:15][N:14]=[C:13]([CH3:16])[C:12]=2[N+:17]([O-])=O)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[NH:15][N:14]=[C:13]([CH3:16])[C:12]=2[NH2:17])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

参加物

4

反応物 1

HCID 178489097HCID 178489097、化合物

生成物 1

HCID 178489090HCID 178489090、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

4.84 g of 5-(3,4-dimethoxyphenyl)-3-methyl-4-nitro-1H-pyrazole (43) were dissolved in 80 ml of ethanol, and 0.5 g of Pd/C was added to this solution. The solution was shaken under hydrogen for 2 h, then filtered through magnesium sulfate and subjected to rotary evaporation. The residue was chromatographed through silica gel (ethyl acetate/heptane 3/1). The following was obtained: 44 C12H15N3O2 (233.27); MS (ESI) 234 (M+H)

後処理

  1. filtrationfiltered through magnesium sulfate
  2. customsubjected to rotary evaporation
  3. customThe residue was chromatographed through silica gel (ethyl acetate/heptane 3/1)
  4. customThe following was obtained

出典と根拠

ORDレコード
ord-75c8542bf2744861be4cf955a5e054a5
出典データセット
uspto-grants-2005_01
特許番号
US06841556B2

反応ノート

読み込み中…