HCID 12136946, compound → HCID 12136947, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-(3-fluorophenyl)-1-(6-methoxy-3-pyridyl)-1H-imidazo[4,5-clpyridine-4-amine (290 mL) obtained in Example 42 and conc. hydrochloric acid (10 mL) was stirred at 110° C. for 7.5 hours. The reaction solution was evaporated, and the residue was purified by NH-form silica gel column chromatography, to give the title compound (120 mg, 43%)

Provenance & Evidence