4-(2-Carboxyethoxy)benzoic acid → HCID 13316012, compound

HRID 1760246Notes

Reaction equation

HRID 1760246 reaction equation
[C:1]([C:4]1[CH:15]=[CH:14][C:7]([O:8][CH2:9][CH2:10][C:11]([OH:13])=O)=[CH:6][CH:5]=1)([OH:3])=[O:2]>S(=O)(=O)(O)O>[O:13]=[C:11]1[C:6]2[C:7](=[CH:14][CH:15]=[C:4]([C:1]([OH:3])=[O:2])[CH:5]=2)[O:8][CH2:9][CH2:10]1

Participants

3

Reactant 1

HCID 133160094-(2-Carboxyethoxy)benzoic acid

Product 1

HCID 13316012HCID 13316012, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

3-(4-Carboxyphenoxy)propionic acid (2.5 g) [prepared according to the procedure of J. Lichtenberger and R. Geyer. Bull. Soc. Chim. Fr., 1963 275] in conc. sulfuric acid (20 ml) was heated to 100° C. for 4 h and then poured onto crushed ice. The resultant precipitate was filtered and dried in vacuo to give the title compound (1.6 g).

Workup

  1. additionpoured
  2. customonto crushed ice
  3. filtrationThe resultant precipitate was filtered
  4. customdried in vacuo

Sources & evidence

ORD record
ord-e509a9274bbe4f3483969bfa6195ecfa
Source dataset
uspto-grants-2005_01
Patent number
US06841560B2

Reaction notes

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