HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isobutyrylacetate → HCID 178439454, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isobutyrylacetate | HCID 81583 | — |
| Reactant | 4-Chlorobenzene-1-carboximidamide hydrochloride | HCID 203436 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178439454 | HCID 178439454 | — |
Reaction Steps
A mixture of 19.1 g of 4-chlorobenzamidine hydrochloride, 15.8 g of ethyl 4-methyl-3-oxopentanoate, 11.2 g of potassium tert-butoxide and 200 ml of ethanol was heated under reflux for 2 hours. After cooling to room temperature, the solid was filtered off with suction, washed with water and with a little ethanol and dried at 40° C. in vacuo. Yield: 12.5 g. M.p.: 164° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06844347B1 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-9baea337a658411799a712625b99e8cc |
| Source note | uspto-grants-2005_01 |