HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68890109, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl methyl ether | HCID 15413 | — |
| Reactant | HCID 20824954 | HCID 20824954 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68890109 | HCID 68890109 | — |
Reaction Steps
The tide compound (ISP-MS: m/e 219.3 ([M+H]+)) was produced in accordance with the general method of example 1a), using tert-butyl-methyl ether instead of tetrahydrofuran as solvent, from (R)-8-fluoro-4,6-dimethyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one. The product (20 mg) was dissolved in dichloromethane and treated with a solution of HCl in diethyl ether to precipitate the hydrochloride salt Yield: 18 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06844345B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-960df21994aa4c69b213d01368bdb643 |
| Source note | uspto-grants-2005_01 |