Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1760593Generated: October 31, 2026

Hydrochloric Acid → HCID 68890109, compound

https://huagongshe.com/reaction/1760593

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantHCID 20824954HCID 20824954—
SolventDiethyl EtherHCID 3283—
SolventDichloromethaneHCID 6344—
ProductHCID 68890109HCID 68890109—

Reaction Steps

The tide compound (ISP-MS: m/e 219.3 ([M+H]+)) was produced in accordance with the general method of example 1a), using tert-butyl-methyl ether instead of tetrahydrofuran as solvent, from (R)-8-fluoro-4,6-dimethyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one. The product (20 mg) was dissolved in dichloromethane and treated with a solution of HCl in diethyl ether to precipitate the hydrochloride salt Yield: 18 mg.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06844345B2
Source datasetuspto-grants-2005_01
ORD IDord-960df21994aa4c69b213d01368bdb643
Source noteuspto-grants-2005_01