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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1760694Generated: October 31, 2026

HCID 21912048, compound → HCID 20745818, compound

https://huagongshe.com/reaction/1760694

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21912048HCID 21912048—
ReactantHCID 86584328HCID 86584328—
SolventTetrahydrofuranHCID 8028—
ProductHCID 20745818HCID 20745818—

Reaction Steps

The title compound was prepared by reacting with 2-(4-chloro-2,6-dimethyl-phenoxy)-4-(1-hydroxymethyl-propylamino)-6-methyl-nicotinic acid with triphosgene/NEt3 in THF. 1H NMR(CDCl3) d 7.18(s,1H), 7.06(s,2H), 5.00(m,1H), 4.64(t,1H), 4.23(dd,1H), 2.339-s,3H), 2.08(s,6H). 1.5-1.8(m,2H), 0.949t,3H) ppm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06844351B1
Source datasetuspto-grants-2005_01
ORD IDord-24a3766d726f4f84836088700a9850b5
Source noteuspto-grants-2005_01