HCID 21912199, compound → HCID 21912168, compound

HRID 1760708Notes

Reaction equation

HRID 1760708 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([O:9][C:10]2[C:15]([CH3:16])=[CH:14][C:13]([CH3:17])=[CH:12][C:11]=2[CH3:18])[C:3]=1[CH2:19][OH:20].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([O:9][C:10]2[C:11]([CH3:18])=[CH:12][C:13]([CH3:17])=[CH:14][C:15]=2[CH3:16])[C:3]=1[CH:19]=[O:20]

Participants

4

Reactant 2

HCID 21912199HCID 21912199, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 21912168HCID 21912168, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared by oxidation of 4-chloro-6-methyl-2-(2,4,6-trimethyl-phenoxy)-pyridin-3-yl-methanol with pyridinium chlorochromate in methylene chloride at room temperature. The desired product was isolated after column chromatography to give a green solid (80% yield). 1H NMR(CDCl3) d 10.66(s, 1H), 6.91(s,3H), 2.31(s,3H), 2.07(s,3H) ppm.

Sources & evidence

ORD record
ord-5eba9c4fcecc46fca6ec37bbed998bea
Source dataset
uspto-grants-2005_01
Patent number
US06844351B1

Reaction notes

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