HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3,4,5-Trisbenzyloxybenzyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (3,4,5-Tris(benzyloxy)phenyl)methanol | HCID 11407668 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3,4,5-Trisbenzyloxybenzyl Chloride | HCID 22593238 | — |
Reaction Steps
40.0 g (0.33 mol) of thionyl chloride are added dropwise at room temperature to a suspension of 12.0 g (0.028 mol) of 3,4,5-trisbenzyloxybenzyl alcohol in 100 ml of diethyl ether. Heating is then carried out at reflux for 2 hours, resulting in a clear solution. After removal of excess thionyl chloride and solvent, the residue is recrystallised from isopropanol/hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06846492B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-efbda141e8764053aec25cfda974ff12 |
| Source note | uspto-grants-2005_01 |