4-Bromotoluene → 1-Benzyl-4-(4-methylphenyl)piperidin-4-ol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH3:8])[cH:6][cH:7]1.[CH2:9]([c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)[N:16]1[CH2:17][CH2:18][C:19](=[O:22])[CH2:20][CH2:21]1>>[c:2]1([C:19]2([OH:22])[CH2:18][CH2:17][N:16]([CH2:9][c:10]3[cH:11][cH:12][cH:13][cH:14][cH:15]3)[CH2:21][CH2:20]2)[cH:3][cH:4][c:5]([CH3:8])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-6d9db5e09ae94788be66d2d239f6b317
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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