反应详情

温度

100 °C

22.4 ml (0.2 mole) of 2-methyiphenol and 34.6 ml (0.4 mole) of ethylene dibromide are mixed and heated at 100° C. The mixture is stirred vigourously with 125 ml 1.6N NaOH, continued heat and stirred till the pH value to 7. Upon cooling, after filtrating the extracted solids, the mixed solution's organic layer is extracted with chloroform and rinsing the extracted solids with NaCl and MgSO4. The generated product is filled into silica gel chromatography columns. The mixture solution of Hexane and Ethylacetate was used as the eluent solution. Upon purification, until white crystallization 2-methyphenoxy)ethylbromide are obtained.

1. temperaturecontinued heat
2. temperatureUpon cooling
3. filtrationafter filtrating the extracted solids
4. extractionthe mixed solution's organic layer is extracted with chloroform
5. washrinsing the extracted solids with NaCl and MgSO4
6. additionThe generated product is filled into silica gel chromatography columns
7. customUpon purification
8. customuntil white crystallization 2-methyphenoxy)ethylbromide
9. customare obtained