2H-Azepine, 3,4,5,6-tetrahydro-7-methoxy- → HCID 22594345, compound

Participants

Reaction Steps

A solution of N-tert-butoxycarbonyl-1,3-propanediamine (2 g; 11.48 mmol), described in Step a of Preparation A, in 1 ml of ethanol is added to a solution of 2-methoxy-4,5,6,7-tetrahydro-3H-azepine (1.46 g; 11.48 mmol; 1.7 ml) in 4 ml of absolute ethanol. After stirring for 8 hours at ambient temperature, the reaction mixture is concentrated to yield the expected product.

Provenance & Evidence