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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1761099Generated: October 30, 2026

ethyl 1-methyl-1H-indole-2-carboxylate → 1-Methyl-2-(methylamino methyl)-6-methoxy-1H-indole

https://huagongshe.com/reaction/1761099

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl 1-methyl-1H-indole-2-carboxylateHCID 143368—
Reactant6-Methoxy-N,1-dimethyl-1H-indole-2-carboxamideHCID 17930109—
Product1-Methyl-2-(methylamino methyl)-6-methoxy-1H-indoleHCID 2259374895%

Reaction Steps

N, 1-Dimethyl-6-methoxy-1H-indole-2-carboxamide According to the procedure of Preparation 1(b), except substituting methyl-1-methyl-6-methoxy-1H-indole-2-carboxylate for ethyl-1-methyl-1H-indole-2-carboxylate, the title compound (95%) was prepared as an off-white solid: MS (ES) m/e 219.2 (M+H)+ and 437.4 (2M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06846819B1
Source datasetuspto-grants-2005_01
ORD IDord-36d2038f7ea54a9f8a869f98df6b0460
Source noteuspto-grants-2005_01