HRID1761388

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=CCOC(=O)O[C@H](C)[C@H]1C(=O)N(C(C(=O)OCC=C)=P(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@H]1S

HCID14084562

未命名化合物

HCID22721631

6-Methylpyridine-3-carbonyl chloride--hydrogen chloride (1/1)

C7H7Cl2NO

PRODUCTS

生成物

结构：C=CCOC(=O)O[C@H](C)[C@H]1C(=O)N(C(C(=O)OCC=C)=P(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@H]1SC(=O)c1ccc(C)nc1

HCID56986149

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23954

Silver

PROCEDURE

实验过程

0.415 g of the silver salt of 2-[(3S,4R)-3-[(1R)-1-allyloxycarbonyloxyethyl]-4-mercapto-2-oxo-azetidin-1-yl]-2-triphenylphosphoranylideneacetic acid allyl ester and 0.18 g of 6-methylnicotinoyl chloride hydrochloride are converted into the title compound analogously to Example 1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bb5b86a0397045419c2361614eb4cf94
来源数据集: uspto-grants-1989_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04826832
来源说明: uspto-grants-1989_05

反应 SMILES

[CH2:1]([O:4][C:5](=[O:41])[C:6]([N:26]1[C@H:29]([SH:30])[C@@H:28]([C@H:31]([O:33][C:34]([O:36][CH2:37][CH:38]=[CH2:39])=[O:35])[CH3:32])[C:27]1=[O:40])=[P:7]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH:2]=[CH2:3].Cl.[CH3:43][C:44]1[CH:52]=[CH:51][C:47]([C:48](Cl)=[O:49])=[CH:46][N:45]=1>[Ag]>[CH2:1]([O:4][C:5](=[O:41])[C:6]([N:26]1[C@H:29]([S:30][C:48](=[O:49])[C:47]2[CH:51]=[CH:52][C:44]([CH3:43])=[N:45][CH:46]=2)[C@@H:28]([C@H:31]([O:33][C:34]([O:36][CH2:37][CH:38]=[CH2:39])=[O:35])[CH3:32])[C:27]1=[O:40])=[P:7]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH:2]=[CH2:3]