HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diketene → HCID 131715933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diketene | HCID 12661 | — |
| Reactant | N-Piperidinoethanol | HCID 18232 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 131715933 | HCID 131715933 | — |
Reaction Steps
Diketene (8.1 ml) was added dropwise to 2-piperidinoethanol (9.36 ml) and triethylamine (0.05 ml) under stirring, so as to keep the temperature at 60°-70° C. (exothermic reaction). When the addition was over, the mixture was stirred at 80° for 40'. 12.4 g of the product were obtained by vacuum (2 mmHg) distillation. The NMR spectrum was in agreement.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04826856 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-225ff68748c043408501038139a31dfe |
| Source note | uspto-grants-1989_05 |