HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(3-Chloro-4-fluorophenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-Chloro-4-fluoroaniline | HCID 9708 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-(3-Chloro-4-fluorophenyl)acetamide | HCID 589188 | — |
Reaction Steps
To 3-chloro-4-fluoroaniline (100 g) was slowly added acetic anhydride (200 ml). After allowed to stand for 30 minutes, the reaction mixture was poured into water (1 litter). The resulting precipitate was collected by filtration and recrystallized from aqueous ethanol to give the title compound (119.4 g), mp 118°-119° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04826982 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-5e5001753cee4cfdbeb924443d6973e6 |
| Source note | uspto-grants-1989_05 |