HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Bromo-2,4,5-trifluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Bromo-2,4,5-trifluorobenzoic acid | HCID 2783246 | — |
| Product | 3-Bromo-2,4,5-trifluorobenzoyl chloride | HCID 13748802 | — |
Reaction Steps
A solution of the 3-bromo-2,4,5-trifluorobenzoic acid (2.5 g) in thionyl chloride (10 ml) was refluxed for 2.5 hours, and then concentrated. The resulting residue was purified by distillation through Widmer fractionating column to give the title compound (2.3 g), bp 98°-102° C./18 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04826982 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-e7c2bcbdd9f2453ebd6e159b46ed4b38 |
| Source note | uspto-grants-1989_05 |