Sodium → HCID 178461713, compound

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Reaction Steps

Taurocholic acid, sodium salt, was converted to a free acid form by the procedure of Example 11. About 100 mg by weight of the free acid form was mixed with 20 mg of dry minoxidil in 1 ml pH 5.5 buffer, yielding a clear solution with a final minoxidil concentration of about 2% by weight. Stirring was continued until a clear solution was obtained, after which the pH of the solution was readjusted to 5.0. No crystals were observed on examination of the composition with a polarizing microscope.

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