HCID 19888656, compound → HCID 19888657, compound

HRID 1761871Notes

Reaction equation

HRID 1761871 reaction equation
[CH3:1][N:2]([CH:16]1[CH2:24][C:23]2[C:18](=[CH:19][CH:20]=[C:21]([N+:25]([O-])=O)[CH:22]=2)[CH2:17]1)[CH2:3][C:4]1[O:5][C:6]2[CH:12]=[CH:11][C:10]([N+:13]([O-])=O)=[CH:9][C:7]=2[CH:8]=1>C(O)C.[Pd]>[NH2:25][C:21]1[CH:22]=[C:23]2[C:18](=[CH:19][CH:20]=1)[CH2:17][CH:16]([N:2]([CH2:3][C:4]1[O:5][C:6]3[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][C:7]=3[CH:8]=1)[CH3:1])[CH2:24]2

Participants

4

Reactant 1

HCID 19888656HCID 19888656, compound

Product 1

HCID 19888657HCID 19888657, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 2-[N-methyl-N-(5-nitrobenzofur-2-ylmethyl)amino]-5-nitroindane (0.33 g) in ethanol (25 ml) containing 5% Pd/C (0.03 g) was stirred under a hydrogen atmosphere [206.8 kPa (30 p.s.i.)] for 3 hours at room temperature. The catalyst was then removed by filtration and the filtrate evaporated in vacuo to afford the title compound as a gum, yield 0.3 g, which was used directly without further purification.

Workup

  1. customThe catalyst was then removed by filtration
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-127c9f1e4cb345f287e0b4022f7dfd86
Source dataset
uspto-grants-1989_05
Patent number
US04829071

Reaction notes

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