HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Methyl 5-chloro-3-formyl-2-hydroxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 5-Chloro-3-formyl-2-hydroxybenzoic acid | HCID 183356 | — |
| Product | Methyl 5-chloro-3-formyl-2-hydroxybenzoate | HCID 13146779 | — |
Reaction Steps
193 g of 5-chloro-3-formyl-2-hydroxybenzoic acid are dissoved in 2 liters of methanol and the solution is saturated with hydrogen chloride. 100 ml of thionyl chloride are added to the solution and the mixture is refluxed for 8 hours. After cooling, the resultant crystals are collected by filtration and dried to give 190 g of methyl 5-chloro-3-formyl-2-hydroxybenzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04829067 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-1e56515e547646cc800282f9f8fb4e31 |
| Source note | uspto-grants-1989_05 |