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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1761971Generated: October 30, 2026

HCID 14500295, compound → [2-tert-Butyl-4-(4-fluorophenyl)-5-phenylfuran-3-yl]methanol

https://huagongshe.com/reaction/1761971

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 14500295HCID 14500295—
ReactantAluminium lithium hydrideHCID 21226445—
SolventDiethyl EtherHCID 3283—
Product[2-tert-Butyl-4-(4-fluorophenyl)-5-phenylfuran-3-yl]methanolHCID 14500301—

Reaction Steps

Under a dry nitrogen atmosphere, to a slurry of 1.15 g (30.4 mmol) of lithium aluminum hydride in 50 ml of dry ether at about 0° was added 5.56 g (15.2 mmol) of 4-(4-fluorophenyl)-2-tert.-butyl-5-phenyl-3-furyl-carboxylic acid, ethyl ester in 25 ml of dry ether. The mixture was heated at reflux for one-half hour.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04829081
Source datasetuspto-grants-1989_05
ORD IDord-4a20bd316a8c4a848c1d797cda85f1ae
Source noteuspto-grants-1989_05