Dimethylformamide → N-[3-ethyl-4-[5-(4-methylphenyl)sulfonyl-1,5,7,10,11-pentazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl]cyclopentyl]azetidine-1-sulfonamide

HRID 176201Notes

Reaction equation

HRID 176201 reaction equation
[CH2:1]([CH3:2])[CH:3]1[CH2:4][CH:5]([NH2:30])[CH2:6][CH:7]1[c:8]1[n:9][n:10][c:11]2[n:12]1[c:13]1[c:14]([n:15][cH:16]2)[n:17]([S:20](=[O:21])(=[O:22])[c:23]2[cH:24][cH:25][c:26]([CH3:27])[cH:28][cH:29]2)[cH:18][cH:19]1.[N:31]1([S:35](=[O:36])(=[O:37])[Cl:38])[CH2:32][CH2:33][CH2:34]1.[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[CH2:1]([CH3:2])[CH:3]1[CH2:4][CH:5]([NH:30][S:35]([N:31]2[CH2:32][CH2:33][CH2:34]2)(=[O:36])=[O:37])[CH2:6][CH:7]1[c:8]1[n:9][n:10][c:11]2[n:12]1[c:13]1[c:14]([n:15][cH:16]2)[n:17]([S:20](=[O:21])(=[O:22])[c:23]2[cH:24][cH:25][c:26]([CH3:27])[cH:28][cH:29]2)[cH:18][cH:19]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 55280383Azetidine-1-sulfonyl chlorideHCID 580098883-Ethyl-4-(6-tosyl-6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-1-yl)cyclopentanamine

Product 1

HCID 178436845N-[3-ethyl-4-[5-(4-methylphenyl)sulfonyl-1,5,7,10,11-pentazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl]cyclopentyl]azetidine-1-sulfonamide

Sources & evidence

ORD record
ord-680ad631500744f19489eb567b7ae7fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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