2-Methyl-2H-pyrazol-3-ylamine → 5-Isothiocyanato-1-methyl-1H-pyrazole

HRID 1762028Notes

Reaction equation

HRID 1762028 reaction equation
NC1N(C)N=CC=1.[CH3:8][N:9]1[C:13]([NH:14][C:15](=S)[SH:16])=[CH:12][CH:11]=[N:10]1>C(N(CC)CC)C>[CH3:8][N:9]1[C:13]([N:14]=[C:15]=[S:16])=[CH:12][CH:11]=[N:10]1

Participants

4

Reactant 2

HCID 1369272-Methyl-2H-pyrazol-3-ylamineHCID 14516770HCID 14516770, compound

Product 1

HCID 142527625-Isothiocyanato-1-methyl-1H-pyrazole

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Using 5-amino-1-methylpyrazole as a starting material, triethylamine salt of 1-methyl-5-pyrazolyldithiocarbamic acid (m.p.: 89° to 94° C.) was synthesized, following the procedures described in Reference Example 1. Ferric chloride was allowed to act upon the resulting product to yield the desired compound. Oily substance.

Workup

  1. customwas synthesized

Sources & evidence

ORD record
ord-e74b165e0c4145af816638c1f38bf441
Source dataset
uspto-grants-1989_05
Patent number
US04830660

Reaction notes

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