Phenylacetyl chloride → HCID 135767482, compound

Participants

Reaction Steps

A mixture of 2-(2-fluorophenyl)-7,8,9,10-tetrahydropyrido[3,4-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)one (0.57 g, Example 15) and phenylacetylchloride (3 mL) is heated under nitrogen at 120° for 4 hours. The mixture is diluted with ether (30 mL) and the solid collected, washed with ether and air dried to afford pure 9-phenylacetyl-2-(2-fluorophenyl)-7,8,9,10-tetrahydropyrido[3,4-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)one, m.p. 310°-313°, in 85% yield.

Provenance & Evidence