反应详情

A solution of 2-formamido-6-methylbenzyl alcohol (1.9 g) in tetrahydrofuran (26 ml) was added dropwise to a suspension of lithium aluminum hydride (0.873 g) in tetrahydrofuran (17 ml) at room temperature over a period of 10 minutes. After being refluxed for 4.5 hours, the excess reagent was decomposed with a small amount of water and the resulting precipitates were filtered off by suction. The filtrate was evaporated in vacuo and the residue was recrystallized from carbon tetrachloride to give 6-methyl-2-methylaminobenzyl alcohol (0.86 g).

1. temperatureAfter being refluxed for 4.5 hours
2. customthe resulting precipitates
3. filtrationwere filtered off by suction
4. customThe filtrate was evaporated in vacuo
5. customthe residue was recrystallized from carbon tetrachloride