Hydrochloric Acid → HCID 20042545, compound

Participants

Reaction Steps

To a suspension of 8-[2,6-bis(hydroxymethyl)benzyloxy]-2-methyl-3-(2-propynyl)imidazo[1,2-a]pyridine (4.9 g) in methanol (80 ml) was added 1 N hydrochloric acid (15 ml) at room temperature. The obtained clear solution was concentrated under reduced pressure and the residue was recrystallized from a mixture of acetone (100 ml) and water (8 ml) to give 8-[2,6-bis(hydroxymethyl)benzyloxy]-2-methyl-3-(2-propynyl)imidazo[1,2-a]pyridine hydrochloride (4.44g)

Provenance & Evidence